French Civilization Essay Example | Topics and Well Written Essays - 500 words

French Civilization - Essay Example There were movements from the east and into France due to food shortages as population increased, the new people brought in new cultures which instead of replacing existing cultures the two cultures were incorporated, Romans brought in major changes in the region which include writing. Industries also emerged which include tool making industries, weaving, pottery and milling The Chasseyan culture existed in the year 3800 BC to 2700 BC and this saw the transformation of people from predators to more settled farming and herding, the Seine Olsen Mane culture existed in the year 3500 to 1800 BC and is said to have originated from northern France and during these years it spread wide in the region, the bell beaker culture is said to have originated from Spain and was characterized by the decoration of utensils. Celts invaded the north in 725 BC and they brought in iron ploughs that helped boost agriculture, Celts also introduced hierarchical form of society where the social groups included warriors, tenants, clients and slaves. The Romans settled in Gaul and brought in major changes to existing cultures which include introduction of taxes, markets, officials, soldiers.

A Key Point to Have a Good Suny College Essay

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Gene Silencing at the Nuclear Periphery Essay Example | Topics and Well Written Essays - 1000 words

Gene Silencing at the Nuclear Periphery - Essay Example Some epigenetic abnormalities have been identified in human tumors, offering tremendous scope for epigenetic modulation as part of cancer chemotherapy. (TY Kim, YJ Bang, KD Robertson, 2006) Histones are small, basic proteins which bind to DNA, to form nucleoproteins - this helps the DNA to be packed tightly into coiled coils. Histones are rich in the amino acids arginine and lysine. Unlike most proteins, histones are water soluble. The functions of histones include packing nucleoproteins for compaction, and chromatin regulation. Histones undergo modifications; this set of modifications which are interdependent and responsible for controlling gene activity is called the "Histone code". The histone code theory of gene regulation was articulated by David Allis and colleagues. According to this theory, expression of certain regions of DNA is turned on and off by histone code. Histone proteins are one of the most highly conserved proteins in eukaryotes, emphasizing their importance in cell biology. Heterochromatin is the condensed, dense form of chromatin, which is transcriptionally inactive; hence it is peripherally located. It is abundantly seen in resting or reserve cells. It stains deeply during interphase (resting stage). The heterochromatin part of a chromosome either lacks genes or has repressed genes. Heterochromatin is seen in both pro and eukaryotes. Euchromatin is delicate, thread-like, active form of chromatin. It is abundant in active, transcribing cells. The importance of euchromatin is because the portion of the DNA coil intended for transcription must uncoil, to permit reading of the code. It stains lightly and its gene concentration is high. It is usually under active transcription and hence it is partially or fully uncoiled. Prokaryotes have only euchromatin. NUCLEAR LOCALISATION - ROLE IN GENE EXPRESSION The vital facts about gene silencing are: (Shaklai et al, 2007) 1. Chromosomes rich in genes are centrally located in the nucleus. Conversely, gene poor ones are located in the periphery. 2. Inactive genes are silenced and translocated to the periphery. 3. If chromatin is moved to the periphery, it is silenced and rendered inactive. Gene silencing plays an important role in determining the fate of different cell lines during development and defining their temporal order. (Fischer, Merkenschlager 2002) cDNA MICROARRAY TECHNIQUE cDNA microarray (c -complimentary) is a tool which helps us analyze and measure the activity of genes. This is done using the process of molecular hybridization. Adenine and thymine are complimentary; Guanine and cytosine are complimentary. While studying two pieces of DNA, if they hybridize (bind to one another), then we can conclude they are complimentary strands - opposite strands of a single gene. Conversely, if they do not hybridize, then they are unrelated. Microarray expression technique has many applications - Gene expression profiling (comparing gene expressions in normal and abnormal cells), study of multigenic diseases like Parkinson's disease,detection of

A Review of Websites for College Students Research Papers

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The New Angle On Title Page Research Paper Mla Just Released

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